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American Diabetes Association - Incretins

There was a lot of news at the ADA meeting on both drugs and devices, but one area that really stood out was the new incretins – approved and on the horizon. Some of these offer three advantages: lower HbA1c, weight loss, and easier dosing. There were also some very early but promising data on islet cell therapy for Type 1 diabetes.

White House Monkeypox Update

Biden administration officials, in a zoom conference with reporters, discussed the monkeypox outbreak and the actions they are taking to combat it, including increasing orders for vaccines and tests. However, they also left a lot of questions unanswered.

Virus Update

What virus should you be worried about today – coronavirus (Covid-19), monkeypox, adenovirus (hepatitis), bird flu, or the latest, Powassan virus? And there are others. For more than two years, coronavirus dominated the news, but recently several old – but serious – viruses have popped up in the news. Here is an update on each of these, with the key takeaways and things to know.

ASCO Preview

The American Society of Clinical Oncology (ASCO) meeting will take place June 3-7, 2022. Here is a report on what ASCO officials previewed for the meeting. They focused on equity, not the expected clinical trials.

ASGCT News

It was clear at the American Society of Gene and Cell Therapy (ASGCT) meeting that cell and gene therapies are alive and well, with many trials in progress. Late-breaking (but early-stage) data were uniformly positive. And officials from the FDA and the EMA explained the regulatory changes affecting the field that they expect as the pandemic winds down. In the EU there will be an end to rolling review, more focus on GMO and durability, and more flexibility but no conditional approvals. The FDA may consider pilots, likely will continue accelerated approvals and surrogate endpoints, and wants to improve review consistency, but sees reimbursement remaining an issue.

Covid Update -- May 2022

More than 6 million people have died worldwide, and nearly a million of those have been in the U.S. Here is the latest news of interest on regulatory actions, Covid-19 side effects, testing, treatment, vaccines, and variants – plus answers to a number of questions about Covid-19 vaccines, testing, and treatment from a panel of experts arranged by the International Antiviral Society-USA (IAS-USA).