Trends-in-Medicine


 
Publisher:  Stephen Snyder
  
Writers:  Lynne Peterson
 Marta Weber
 Diana Woods
  
Editors:  Kathleen Snyder
 Betty Teel
 


Trends-in-Medicine has no financial connections with any pharmaceutical or medical device company. The information and opinions expressed have been compiled or arrived at from sources believed to be reliable and in good faith, but no liability is assumed for information contained in this newsletter.

Copyright©  2004
No articles may be reproduced without written permission of the publisher.


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November 2004 Issues

The Family Medicine Perspective - Quick Pulse

Summary: Family medicine doctors often write more prescriptions for particular medicines than their specialist counterparts, so understanding their attitudes toward a variety of topics and their clinical practices are very important in determining the outlook for new drugs and devices as well as expanded labels for existing products. At the American Academy of Family Practice (AAFP) annual meeting in Orlando, FL from October 13-17, 2004, 21 primary care doctors were questioned on a variety of topics, from antidepressants and diet drugs to medications to treat hyperlipidemia, diabetes, and excessive daytime sleepiness.

The Future of AstraZeneca’s Crestor - Quick Pulse

Summary: As of the end of November 2004, the FDA still had not responded to a consumer watchdog organization’s petition in March 2004, asking the FDA to remove AstraZeneca’s Crestor (rosuvastatin) from the market. The FDA is supposed to respond to petition like this within six months, in this case by September 3, 2004, but there is no penalty for taking longer. Predicting what the FDA will do in this case is difficult, but the issue gained new visibility recently when an FDA official told a congressional committee that he had safety concerns about Crestor.

The Cardiovascular Safety of Cox-2 Inhibitors - Quick Pulse

Summary: With Merck’s Vioxx (rofecoxib) now off the market, how safe are the other Cox-2 inhibitors on the market – Pfizer’s Celebrex (celecoxib) and Bextra (valdecoxib)? What do the cardiovascular problems with Vioxx mean for other Cox-2 inhibitors in development, including Merck's Arcoxia (etoricoxib) and Novartis’s Prexige (lumiracoxib)? There is no easy or quick answer, and this issue may haunt these products for some time.

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